Description
Suture Substance Suture Substance
Polydioxanone monofilament synthetic absorbable sutures are made from a polyester called poly (p-dioxanone). The molecular formula of the polymer is empirical. It is worth noting that the polydioxanone polymer has been found to be non-antigenic and causes only a minimal tissue reaction during the absorption process. Surgexon Polydioxanone sutures meet the standards set by the current edition of the United States Pharmacopeia.
Instructions for Use Instructions for Use
Polydioxanone monofilament synthetic absorbable sutures are recommended for general soft tissue approximation. They can be used in various surgical procedures, including pediatric cardiovascular tissue where growth is anticipated and ophthalmic surgery.
Actions Actions
The in vivo performance of absorbable sutures is determined by two key characteristics: tensile strength retention and absorption rate (loss of mass). POLYDIOXANONE synthetic absorbable sutures have been specifically designed to minimize variations in these characteristics and offer support to wounds throughout an extended healing period. Implantation studies have demonstrated that the absorption of these sutures is minimal until approximately the 90th day after implantation. Absorption is typically fully completed within a timeframe of 180-220 days.
Surgexon's Polydioxanone suture is a sterile, absorbable surgical suture made from the polyester poly(pdioxanone). It has been determined that Surgexon's Polydioxanone is no antigenic and causes minimal tissue reactivity during the absorption process. Clinical trials have demonstrated that after two weeks, around 75-80% of the initial strength of Surgexon's Polydioxanone is retained. After four weeks, approximately 65-70% of the initial strength remains, and at six weeks, around 55-60% remains. The complete absorption of Surgexon's Polydioxanone typically takes place within a period of 180-220 days.
- Surgexon's Polydioxanone sutures are available in both violet and colorless options.
- Surgexon's Polydioxanone is particularly suitable for internal tissues where a long-lasting and absorbable suture is desired.
- Compared to natural absorbable sutures, Polydioxanone, being composed of synthetic materials, elicits less tissue reactivity. However, due to its extended absorption period, some tissue reactivity may still occur.
- The safety and effectiveness of POLYDIOXANONE sutures have not been established for use in neural tissue, adult cardiovascular tissue, or microsurgery.
- In certain circumstances, especially in orthopedic procedures, the surgeon may choose to use external support for immobilization.
- It is important not to re-sterilize Polydioxanone sutures as it may compromise their safety and effectiveness.
Precautions Precautions
- Proper placement of knots is crucial to ensure the security of POLYDIOXANONE sutures.
- Like other synthetic sutures, achieving knot security requires using the standard surgical technique of flat and square ties, with additional throws if necessary based on the surgical circumstances and the experience of the operator.
- When handling any suture, it is important to exercise caution to avoid causing damage.
- It is advisable to avoid applying excessive pressure or crimping with surgical instruments such as needle holders and forceps to the strand, except when grasping the free end of the suture during an instrument tie.
- Conjunctiva and vaginal mucosal sutures that remain in place for prolonged periods may lead to localized irritation and should be removed as directed.
- Sub-cuticular sutures should be placed as deeply as possible to minimize the typical redness and hardening associated with absorption.
- It is essential to follow acceptable surgical practices when it comes to drainage and closure of infected wounds.
Adverse Reactions Adverse Reactions
The extended absorption period of Polydioxanone sutures may result in some irritation and bleeding in the conjunctiva and mild irritation in the vaginal mucosa.
Polydioxanone, PX Polydioxanone, PX
Polydioxanone sutures are especially beneficial in cases where both absorbability and prolonged wound support (up to six weeks) are desired.
Storage Storage
Keep the packaged item stored below 40℃, ensuring it is protected from moisture and direct heat. Refrain from using it past the expiration date.
Brand Name Length Size
| Brand Name | Suture Material | Length | Size | ||||||||||||||
| SurgeDOX | Polydioxanone |
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